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Bone Marrow Transplant in India

Avg Price: $ 9500 - $ 55000

Bone Marrow Transplant, often known as a Hematopoietic Progenitor Cell Transplant (HPSCT), involves giving patients viable Hematopoietic (Blood Cell forming) progenitor cell...
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  • 4-5 Months

    Treatment Time

  • 1 Month

    Recovery Time

  • 20-25 Days

    Hospitalization Days

  • 85-90%

    Success Rate

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Bone Marrow Transplant Treatment, Cost in India

95% Success Rate
11000+ Doctors
150+ Top Hospitals
250+ Surgeries
35+ Countries
95% Success Rate
11000+ Doctors
150+ Top Hospitals
250+ Surgeries
35+ Countries

Overview

Over the past forty years, Bone Marrow Transplant (BMT) has advanced significantly in India. There are ample opportunities that can improvise it further, making it more accessible. To make BMT a very cost-effective procedure for treating patients with a variety of blood disorders, newer strategies are being developed at multiple levels. 

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Types of Bone Marrow Transplant (BMT)

There are different categories of Bone Marrow Transplants based on the source of the donor. These types include:

  • Autologous Bone Marrow Transplant: "Auto" refers to "self." It is also called rescue Transplant. Before receiving high-dose Chemotherapy or Radiation Therapy, progenitor cells are extracted from the patient and stored in the freezer. These blood-forming cells are reintroduced to create healthy blood cells in your body. 
  • Allogeneic Bone Marrow Transplant: “Allo” refers to “other”. Another individual (donor) donates Progenitor cells. The donor's genes must typically at least partially match your DNA. Most frequently, a brother or sister will make a perfect match. Sometimes, parents, kids, and other relatives make compatible matches also. 
  • Umbilical Cord Blood Transplant: It is a kind of Allogeneic Transplant. Progenitor cells are extracted from a newborn baby's umbilical cord shortly after delivery. The progenitor cells are frozen for preservation until there is a need for a Transplant. 
  • Haploidentical Transplant: This is a form of Allogeneic Transplant when the donor and recipient are not perfectly matched. A family member's organs may be used in a haploidentical transplant. Parents and children are never a perfect match. There is a 50% probability that siblings will complement one another. 

Pre-Evaluation

A Pre-Transplant assessment before a Blood or Marrow Transplant is authorised as a course of treatment. This assessment entails a thorough physical examination, discussions with the transplant team, and a comprehensive series of tests to determine whether you are qualified for a Bone Marrow Transplant. These tests may include:

  • Blood Tests
  • Urine Analysis
  • Bone Marrow Aspiration and Biopsy
  • Chest X-Ray
  • Sinus X-Rays
  • Pulmonary Function Tests (PFTs)
  • Computed Tomography (CT Scan)
  • Electrocardiogram (ECG)
  • Cardiac Scan

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Process/ How Is it Done?

An Intravenous Catheter, a long, thin tube is implanted in a big vein in your neck or chest. The Catheter, which is also referred to as a central line, is often left in its position during your therapy. The central line will be used by the Transplant team to inject drugs, blood components, and the Transplanted progenitor cells into your body.

  • Progenitor cell collection for Autologous Transplant: You will go through an apheresis treatment to obtain blood progenitor cells if an autologous Transplant (using your own progenitor cells) is planned. Prior to apheresis, you will get daily growth factor injections to encourage the production of additional progenitor cells and to aid their entry into your bloodstream for removal. During apheresis, blood is drawn from a vein and circulated via a machine. The machine separates your blood into a variety of components, including progenitor cells. For later use, these cells are collected and preserved. The extra blood is reabsorbed by your body.
  • Progenitor cell collection for Allogeneic Transplant: You'll need a donor if you're getting an allogeneic transplant, which uses progenitor cells from a donor. These cells are extracted from the blood or bone marrow of the selected donor.

Complications

Complications after Bone Marrow Transplant may be acute (occurring within 90 days) or chronic (long-standing). These are as follows:

  • Infection: Since the immunosuppression occurs after a Bone Marrow Transplant, antimicrobial prophylaxis is very necessary.
  • Sinusoidal Obstruction Syndrome (SOS): This syndrome is characterized by tender liver enlargement, jaundice, ascites, and weight gain due to fluid retention. As per reports, 13.6% of patients suffer from this syndrome after BMT.
  • Idiopathic Pneumonia Syndrome (IPS): It is a lung infection that generally occurs in the first 90 days post-transplant.
  • Graft Rejection or Failure: Graft Rejection or Failure is the loss of bone marrow function following reconstitution after hematopoietic progenitor cell infusion or the absence of an increase in function.
  • Graft Versus Host Disease (GVHD): Graft Versus Host Disease (GVHD) is caused by a reaction between T Lymphocytes from the donor in an Allogeneic Transplant and the recipient's certain genes, resulting in a slew of symptoms and manifestations.
  • Toxicity: Post-Transplant immunosuppression, can cause severe pancytopenia (significant reduction in Blood Cell count) in the first week after Bone Marrow Transplant, leading to life-threatening infection.

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Post-Procedure

Blood tests and other tests will be performed in the days and weeks following your Bone Marrow Transplant to check your condition. You may require medication to treat problems such as Nausea and Diarrhoea.

There will be close medical supervision of you following your Bone Marrow Transplant. You may need to stay in the hospital for several days or longer if you have infections or other issues. You may also require red blood cell and platelet transfusions until your Bone Marrow produces enough of those cells on its own.

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Life after BMT

For months to years following your Transplant, you may be more susceptible to infections or other problems. You must see your doctor frequently for the rest of your life to monitor for late complications.

Success Rate

With a 70% to 90% survival probability with a matched sibling donor and 75% to 85% survival with unrelated donors, transplants are substantially more successful for patients with non-malignant diseases. Survival rates after transplant for patients with acute leukaemia in remission range from 85% to 90% with related donors and 75% to 85% with unrelated donors. Transplanting a patient's own Bone Marrow from an intact bone to a diseased bone (Autologous Bone Marrow Transplant) in conjunction with Chemotherapy has increased survival rates in various malignancies such as Wilms Tumour, Ewing sarcoma, Germ Cell Tumour, and Neuroblastoma.

Treatment Cost Analysis & Comparison

The cost of Bone Marrow Transplant significantly depends upon the patient's Health Status, Patient requirements, Hospital choice, and the availability of treatment options. However, the following information can provide you with a broader view of the cost and expense:

Cost Analysis and comparison based on the type of Bone Marrow Transplant:

Type of procedure Approximate cost of bone marrow transplant
Autologous bone marrow transplant $ 9500 onwards
Allogeneic bone marrow transplant $ 24000 onwards
Haploidentical transplant $ 35000 onwards

Cost Analysis and comparison based on the location of a Bone Marrow Transplant Centre:
 

Price Approximate cost of Bone Marrow Transplant
Bone Marrow Transplant Cost in Delhi NCR $ 11,000-$ 55,000
Bone Marrow Transplant Cost in Mumbai $ 10,500-$ 48,000
Bone Marrow Transplant Cost in Chennai $ 9500-$ 52000
Bone Marrow Transplant Cost in Bangalore $ 10000-$ 45000

Factors Affecting Cost

The common drivers of overall expenses are due to the following factors:

  • Hospitalisation: The major cost contributors are associated with the length of Hospital stay, Medical staff, Rooms, Laboratory, Pharmacy, Radiology, Blood Bank, and Blood products
  • Complication Treatment: As per a study, the average cost per complication is $20,228. Lowering the risk of severe complications may reduce overall expenses.
  • Transplantation For More Advanced Disease: The disease status also influences the cost of bone marrow transplant. According to research, patients with advanced disease had higher expenditures.

Cost of Diagnostics

In India, a bone marrow test might cost anywhere approximately from $100 to $500. However, the price of a bone marrow test in India varies significantly depending on the following factors:

  • Facility type (public or private)
  • City or patient's location
  • Test's accessibility

Our Services

MedFlick, your trusted healthcare companion, is dedicated to ensuring that your medical journey goes as smoothly and successfully as possible.

  • Individualized Guidance: Personalized guidance throughout your medical journey. Access to a broad network of prominent hospitals, top doctors, and skilled surgeons.
  • Transparent and Competitive Pricing: A full breakdown of treatment costs that eliminates surprises and offers you cost-effective solutions. MedFlick provides everything from travel arrangements to hotel and visa help to lodging.
  • Multilingual Support: Breaking down language barriers to allow patients and medical professionals to communicate more effectively. The road to a successful Bone Marrow Transplant is long and winding, full of hope, resilience, and the promise of a brighter future. With MedFlick as your guide, navigating this life-changing adventure becomes simple and liberating.

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Can a family member who has a partial HLA match be an acceptable donor for a Bone Marrow Transplant, or is it necessary to find a fully matched unrelated donor?

A family member who has a partial HLA (Human Leukocyte Antigen) match may be an acceptable donor for a Bone Marrow Transplant, particularly if a fully matched unrelated donor is not available. While a fully matched donor is preferred to reduce problems and graft failure, a partial match from a family member can still be considered if the HLA match is close enough. The decision on the donor will be based on the patients individual condition and the medical team's recommendations.

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Are there any special lifestyle adjustments or measures I should take following a Bone Marrow Transplant to ensure success?

Following a Bone Marrow Transplant, patients must take a number of precautions to reduce the risk of infection and complications. These could include avoiding crowds and sick people, practising good hand cleanliness, adhering to a particular diet to prevent foodborne infections, and following the medication regimen advised by the medical team. Regular check-ins with the healthcare team are required to monitor progress and address any concerns as soon as possible.

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Frequently asked questions

How long does it take to recover after a BMT?
How to find the right Bone Marrow Donor?
Is Bone Marrow Transplant always successful?
Can BMT cure Leukemia?
Who can be a 100% match for a Bone Marrow Transplant?
What are the chances of Leukemia relapse after Bone Marrow Transplant?
Who are not the best fits for Bone Marrow donation?
What is the age limit criteria for Bone Marrow donors?
What are the side effects that may appear after donating Bone Marrow?
Who cannot have a Bone Marrow Transplant?

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